THE CYPRUS INSTITUTE OF NEUROLOGY AND GENETICS

P.O.Box 23462

1683 NICOSIA - CYPRUS

Tel: 02-358600

Fax: 02-358237

The Cyprus Institute of Neurology and Genetics (CING) was established in 1990 and has moved to its purpose built premises in 1995. This was made possible following a generous donation by the United States, through the Cyprus office of UNHCR, in order to serve both the Greek and Turkish Cypriots.

The CING is a bicommunal, non-profit medical, diagnostic, research and academic institution. Its staff specializes in neurology, molecular biology and all aspects of genetics. The Institute has an international reputation and works closely with the Cyprus Government, private doctors and scientists as well as other institutions and Universities abroad.

The staff of the CING consists of 99 persons as follows: 13 senior scientists, 9 post-doctorate research fellows, 32 scientific personnel, 20 medical and paramedical personnel, and 28 administrative staff. The total number of Ph.D. holders is 17.

Cyprus is known to have an increased frequency of inherited disorders, which place a heavy burden on the patients? families and the Government. The Institute provides specialized services and research in neurology, genetics, DNA forensics, molecular biology, histopathology and virology. Services and research aim towards early detection and prevention of diseases, the provision of high quality medical services, the analysis of police evidentiary material and in general improvement in the quality of life of the community.

More specifically the Institute is dedicated to lessening the suffering of patients and their families and preventing diseases through patient care, research and teaching programs on neurological and genetic conditions such as muscular dystrophy, multiple sclerosis, epilepsy, malformation syndrome, chromosomal abnormalities and all other aspects of molecular biology and genetics such as thalassaemia, molecular virology, mental retardation, cardiovascular disease, stroke, cystic fibrosis etc. It should be mentioned that more that 5,000 patients visit the Institute every year for a specialized service and treatment, while more that 17,000 samples are tested from the various laboratories of the Institute for neurological and genetic diseases. In addition, the Institute plays a key role in the fight against crime by providing specialized DNA services to Police Authorities and expert court testimony for criminal and civil investigations. The CING provides services, as requested, to all doctors, clinics, hospitals, lawyers and Police Authorities, both private and governmental.

The various departments of the CING have also signed agreements of collaborations both in providing services and diagnostic tests as well as specific research programs with many countries like Turkey, Jordan, Syria, the Middle East countries, Romania, Greece, etc.

Several of the research and teaching programs are carried out in collaboration with institutions and universities both from Cyprus and abroad. For example, the CING is recognized for Ph.D. studies by several Universities around the world, such as the Imperial College of London. Students can pursue their Ph.D. studies at the CING, with joint supervision, and by spending only 40 days a year abroad.

In addition, Greek universities have recognized CING as an academic institution and 3 PhD programs are currently carried out at CING without the candidates having to spend any time abroad. Members of the Scientific Council of CING are the supervisors of these PhD programs and are members of the relevant PhD examination board.

CING has an annual budget of £2,000,000 (year 2000). 75% of the funds are obtained from the Ministry of Health (Cyprus Government) as a subsidy towards the services offered to the public sector. In addition, CING scientists and doctors manage to obtain around £350,000 annually, from competitive grants, from abroad (Europe, United States, Middle East etc).

A unique feature of the Institute is the combination of services and research. In biomedical sciences and medicine the ultimate aim of the research is to solve medical problems and improve the health and quality of life of the community. Services provide the material for such research. The bigger the volume of services the greater is the opportunity for the scientists to come in contact with clinical problems; the bigger is the volume of material available for research the higher are the possibilities to attract major research grants. With major grants, better solutions to clinical problems can be found, resulting in the provision of higher quality services. Thus, both service and research enter in a positive feedback loop. The result is a center of excellence.

As a result of the specialized services carried out at the Institute, substantial financial savings have been achieved by sparing patients and samples from being sent abroad. The CING is in a unique position to serve not only the needs of Cyprus but also the neighboring countries.

Scientists/Group leaders
Field
Contact
  • Cariolou Marios, BSc, PhD 
Molecular Genetics Department B & DNA Identification Lab

Cardiovascular Research, Multifactorial Inheritance and DNA Identification 

Cardiovascular diseases including familial hypercholesterolaemia, stroke and hypertension. DNA typing of biological specimens (Police, paternity and missing persons investigations) 

cariolou@mdrtc.cing.ac.cy
  • Christodoulou Christina, 
BSc, MSc, DEA, PhD
Molecular Virology

Correlation between viral persistent infections in the central nervous system with the Post-Polio Syndrome and the Amyotrophic Lateral Sclerosis

Correlation of some HPV types and cervical ongogenesis. 

cchristo@mdrtc.cing.ac.cy
     
  • Christodoulou Kyproula
BSc, MSc, PhD
Molecular Genetic Department D

Neurogenetics Laboratory

Genetic studies in many neurological conditions (Charcot-Marie-Tooth, heriditary motor neuropathy, myasthenia etc) and genome wide linkage search 

roula@mdrtc.cing.ac.cy
     
  • Deltas Constantinos, 
PharmR, PhD, AIBMS
Molecular Genetics Department C

Molecular Nephrology, Molecular Diagnostics and Research Laboratory 

Diagnosis, prevention and research of hereditary kidney diseases (such as polycystic kidney disease and cystinouria). Also cystic fibrosis, familial mediterranean fever, hereditary thrombophilia and haemochromatosis 

deltasco@mdrtc.cing.ac.cy
     
  • Drousiotou Anthi, 
BSc, PhD, FRCSc
Biochemical Genetics

Diagnosis, monitoring and prevention of inherited metabolic disorders 

anthidr@mdrtc.cing.ac.cy
     
  • Kleanthous Marina
BSc, PhD
Molecular Genetics Department A

Thalassaemia Laboratory

Thalassaemia and other hemoglobin variants

hglobin@mdrtc.cing.ac.cy
     
  • Kyriakides Theodoros, MD
Neuropathology

Molecular and histological diagnostic techniques for neuromuscular and other inherited disorders 

theodore@mdrtc.cing.ac.cy
     
  • Kyriacou Kyriacos, BSc, PhD
Electron Microscopy and Molecular Pathology 

Ultratructure of mitochondrial encepholomyothies and genetics of breast cancer 

kyriacos@mdrtc.cing.ac.cy
     
  • Nicolaides Andis, MS, FRCS
Chairman of the Institute 

Cardiovascular diseases (atherosclerotic and throbotic genes). Cardiovascular screening and stroke prevention various tromboembolism.

anicolai@mdrtc.cing.ac.cy
     
  • Papacostas Savvas, MD
Clinical Neuroscience - Neurophysiology

Electroencephalogram, evoked potentials, nerve conduction velocities, electromyography, Doppler sonography 

savvas@mdrtc.cing.ac.cy
     
  • Patsalis Philippos, 
BSc, MA, Mph, PhD
Cytogenetics

Cytogenetics and Molecular Cytogenetics and Molecular Genetics. Emphasis on mental retardation, reproductive science, and establishing new clinical diagnostic tests 

patsalis@mdrtc.cing.ac.cy
     
  • Leonidas Phylactou, BSc, PhD
Research Group 1

Molecular Function and Therapy

Application of catalytic RNA (ribozymes) to the study and therapy of genetic diseases

laphylac@mdrtc.cing.ac.cy
     
  • Schizas Christos (Honorary)
BSc, MBA, PhD, FBSC, FIEE 
 
  • Pattichis Costantinos (Honorary)
BSc, MSc, PhD, MIEEE, Sen. MIEEE
Computational Intelligence

Development of intelligent systems in medical diagnosis, health telematics, biosignal analysis and medical imaging 

schizas@ucy.ac,cy

pattichi@ucy.ac.cy

     
  • Anastasiadou Violetta, MD
(Honorary)
Clinical Genetics

Reference clinic of the island for genetic disorders (e.g. chromosomal abnormalities, single gene disorders, metabolic disorders, congenital transformations etc) offering diagnosis, treatment and counseling. 

Research in mental retardation, medical ethics etc

genecing@mdrtc.cing.ac.cy
     
  • Santama Niovi, BSc, MSc, PhD
(Honorary)
Research Group 2

Molecular Cell Biology and Nervous System

Molecular cell biology of microtubule-based motor proteins in the mammalian nervous system

santama@ucy.ac.cy



SESAME 2nd SMB Meeting, Nicosia 6-7 December 2000